Mucosa-associated lymphoid tissue (MALT)

Definition

Mucosa-associated lymphoid tissue (MALT) is a component of the immune system that protects mucosal surfaces such as those in the digestive, respiratory, and urogenital tracts. It contains various types of immune cells that detect and respond to pathogens entering through mucosal membranes.

5 Must Know Facts For Your Next Test

1. MALT includes structures like tonsils, Peyer's patches, and the appendix.
2. MALT plays a crucial role in producing IgA antibodies, which are essential for mucosal immunity.
3. MALT can initiate both innate and adaptive immune responses against pathogens.
4. The gut-associated lymphoid tissue (GALT) is a significant part of MALT found in the intestines.
5. Chronic inflammation in MALT can sometimes lead to conditions like MALT lymphoma.

Review Questions

Related terms

Tonsils: Lymphoid tissues located at the back of the throat that are part of MALT.

Peyer's Patches: Small masses of lymphatic tissue found in the small intestine that form an important part of GALT.

IgA Antibodies: Immunoglobulin A antibodies produced by plasma cells in mucosal areas to neutralize pathogens.