Mucin

Definition

Mucin is a glycoprotein that plays a crucial role in protecting and lubricating the respiratory tract. It forms mucus when secreted by goblet cells and submucosal glands.

5 Must Know Facts For Your Next Test

1. Mucin helps trap and remove inhaled particles and pathogens from the respiratory system.
2. It is produced by goblet cells in the epithelial lining of the respiratory tract.
3. Mucin has a high molecular weight and is heavily glycosylated, which contributes to its gel-like properties.
4. In cystic fibrosis, defective mucin production leads to thick, sticky mucus that impairs respiratory function.
5. Mucin production can be upregulated in response to irritants like smoke or allergens.

Review Questions

Related terms

Goblet Cells: Specialized epithelial cells that secrete mucin into the respiratory tract.

Cilia:

Hair-like structures on epithelial cells that help move mucus out of the respiratory tract.

Submucosal Glands: Glands located beneath the mucosal layer that produce mucus containing mucin.