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Introns

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Introns are non-coding sequences of DNA within a gene that are removed during RNA splicing. They do not encode protein sequences and are transcribed into pre-mRNA but not translated into proteins.

5 Must Know Facts For Your Next Test

  1. Introns are found in eukaryotic genes but are generally absent in prokaryotes.
  2. During RNA splicing, introns are removed from the pre-mRNA, and exons are joined together to form mature mRNA.
  3. The presence of introns allows for alternative splicing, which can produce multiple protein variants from a single gene.
  4. Introns often contain regulatory elements that can influence gene expression.
  5. Mutations in intron regions can affect splicing and lead to various genetic disorders.

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