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Hypophyseal portal system

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The hypophyseal portal system is a network of blood vessels that connects the hypothalamus to the anterior pituitary gland. It allows for the direct transport of hormones from the hypothalamus to the anterior pituitary, facilitating rapid and efficient hormonal communication.

5 Must Know Facts For Your Next Test

  1. The hypophyseal portal system consists of two capillary beds connected by portal veins.
  2. It enables hypothalamic hormones to reach the anterior pituitary without entering systemic circulation.
  3. This system is crucial for regulating hormone secretion from the anterior pituitary gland.
  4. Hypothalamic releasing and inhibiting hormones travel through this system to control pituitary function.
  5. Disruption in the hypophyseal portal system can lead to endocrine disorders due to improper hormone regulation.

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