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HIV (human immunodeficiency virus)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

HIV (human immunodeficiency virus) is a virus that attacks the immune system, specifically targeting CD4 cells (T cells), weakening the body's ability to fight infections and diseases. If left untreated, HIV can lead to the disease AIDS (acquired immunodeficiency syndrome).

5 Must Know Facts For Your Next Test

  1. HIV primarily targets and destroys CD4 cells, which are crucial for immune response.
  2. The virus is transmitted through contact with infected bodily fluids such as blood, semen, vaginal fluids, and breast milk.
  3. Antiretroviral therapy (ART) can effectively manage HIV infection and prevent progression to AIDS.
  4. HIV has a high mutation rate, which complicates vaccine development and treatment.
  5. Early detection of HIV through testing is critical for effective management and reducing transmission.

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