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Gene transfer agents (GTAs)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Gene transfer agents (GTAs) are virus-like particles produced by some bacteria that facilitate the horizontal transfer of genetic material between cells. Unlike typical viruses, GTAs do not contain genes for self-replication.

5 Must Know Facts For Your Next Test

  1. GTAs are produced by some bacterial species as a means to transfer DNA between cells.
  2. They play a role in horizontal gene transfer, which is critical for genetic diversity and evolution.
  3. GTAs lack the genes necessary for viral replication, distinguishing them from true viruses.
  4. The transferred DNA can include various genes, potentially aiding in adaptation and survival under different environmental conditions.
  5. Research suggests GTAs may have evolutionary significance in shaping microbial genomes over time.

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