Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
The G0 phase is a period in the cell cycle where cells exist in a quiescent state. Cells in this phase have exited the active cycle and do not prepare to divide.
5 Must Know Facts For Your Next Test
Cells can enter the G0 phase from the G1 phase of the cell cycle.
Some cells, like neurons and muscle cells, remain in G0 permanently.
The G0 phase can be reversible; some cells can re-enter the cell cycle if needed.
G0 is often referred to as a 'resting' phase because cells are not actively preparing for division.
External signals such as nutrients and growth factors can influence whether a cell enters or exits the G0 phase.
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Related terms
G1 Phase: The first stage of interphase where cells grow and prepare DNA replication.
Cell Cycle: A series of stages through which a cell passes to divide and produce new cells.
Quiescence: A state of cellular dormancy where cells are not actively dividing.