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FEV1/FVC ratio

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General Biology I

Definition

The FEV1/FVC ratio is a calculated ratio used in pulmonary function tests to assess the presence of obstructive and restrictive respiratory conditions. It represents the proportion of a person's vital capacity that they can exhale in the first second of forced expiration (FEV1) compared to their total forced vital capacity (FVC).

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5 Must Know Facts For Your Next Test

  1. A normal FEV1/FVC ratio is typically around 70-80% in healthy adults.
  2. A decreased FEV1/FVC ratio indicates obstructive lung diseases such as asthma or chronic obstructive pulmonary disease (COPD).
  3. An increased or normal FEV1/FVC ratio coupled with a reduced FVC suggests restrictive lung diseases like pulmonary fibrosis.
  4. The test involves taking a deep breath and exhaling forcefully into a spirometer to measure both FEV1 and FVC.
  5. The FEV1/FVC ratio helps differentiate between different types of respiratory disorders based on patterns of airflow limitation.

Review Questions

  • What does a decreased FEV1/FVC ratio indicate about lung function?
  • How is the FEV1/FVC ratio measured during a pulmonary function test?
  • Why might an increased or normal FEV1/FVC ratio be seen in restrictive lung diseases?
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