Entamoeba is a genus of parasitic amoebae that primarily inhabit the intestines of humans and other animals. Most notably, Entamoeba histolytica is responsible for amoebic dysentery, a severe intestinal infection that can lead to diarrhea and dysentery. This genus plays a significant role in the context of protists, as it highlights both the diversity of life forms and the impact of certain protists on human health.