🔬general biology i review

Emphysema

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Emphysema is a chronic lung condition that involves the damage and enlargement of the air sacs, or alveoli, in the lungs, leading to reduced oxygen exchange. This disease is primarily caused by long-term exposure to irritants like cigarette smoke and air pollution, which results in a progressive decline in respiratory function. The destruction of alveolar walls causes the lungs to lose their elasticity, making it difficult to exhale air and resulting in breathlessness.

5 Must Know Facts For Your Next Test

  1. Emphysema is often diagnosed using pulmonary function tests that measure lung capacity and airflow rates.
  2. Symptoms of emphysema include shortness of breath, chronic cough, wheezing, and an increased effort to breathe.
  3. The disease progresses slowly, and many patients may not experience significant symptoms until significant lung damage has occurred.
  4. Management of emphysema typically includes lifestyle changes such as quitting smoking, pulmonary rehabilitation, and medications like bronchodilators and steroids.
  5. In advanced cases, supplemental oxygen therapy or surgical interventions like lung volume reduction surgery may be necessary to improve quality of life.

Review Questions

  • What are the physiological changes that occur in the lungs due to emphysema, and how do these changes affect gas exchange?
    • In emphysema, the alveoli become damaged and lose their elasticity, leading to their enlargement and destruction of alveolar walls. This change reduces the surface area available for gas exchange, making it difficult for oxygen to enter the bloodstream and for carbon dioxide to be expelled. As a result, patients experience decreased lung function and increased shortness of breath during physical activities.
  • Discuss how smoking contributes to the development of emphysema and what preventative measures can be taken.
    • Smoking is the primary risk factor for developing emphysema as it introduces harmful chemicals into the lungs that damage the alveolar walls. Over time, this exposure leads to inflammation and destruction of lung tissue. Preventative measures include avoiding smoking or exposure to secondhand smoke, engaging in regular exercise, and maintaining overall lung health through a balanced diet and avoiding environmental pollutants.
  • Evaluate the impact of emphysema on an individual's daily life and discuss potential interventions to manage its symptoms effectively.
    • Emphysema significantly impacts an individual's daily life by limiting physical activity due to breathlessness and chronic fatigue. Patients may find it challenging to perform simple tasks like walking or climbing stairs. Effective management includes interventions such as pulmonary rehabilitation programs that focus on exercise training and education about managing symptoms, medications like bronchodilators that help open airways, and lifestyle changes like smoking cessation which can help slow disease progression and improve quality of life.

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