DNA microarrays

Definition

DNA microarrays are laboratory tools used to detect the expression of thousands of genes simultaneously. They consist of a small solid surface onto which DNA molecules are fixed in an orderly manner.

5 Must Know Facts For Your Next Test

1. DNA microarrays can measure the expression levels of thousands of genes at once.
2. Each spot on a DNA microarray contains multiple identical strands of DNA, representing specific genes.
3. Fluorescent labeling is commonly used to visualize hybridization results on DNA microarrays.
4. DNA microarrays can be used for comparative genomic hybridization and gene expression profiling.
5. They play a crucial role in identifying disease-related gene expression patterns and potential biomarkers.

Review Questions

• What is the main purpose of using DNA microarrays in genomics?
• How are fluorescent labels utilized in DNA microarray technology?
• What types of biological information can be obtained from analyzing DNA microarray data?

Related terms

PCR (Polymerase Chain Reaction): A technique used to amplify small segments of DNA for various genetic analyses.

Next-Generation Sequencing (NGS): Advanced sequencing technologies that allow rapid sequencing of entire genomes or targeted regions.

Gene Expression Profiling: The measurement of the activity (expression) levels of thousands of genes at once to understand cellular function.