Cytopathic effects

Definition

Cytopathic effects are observable changes in host cells due to viral infection. These changes often lead to cell damage or death.

5 Must Know Facts For Your Next Test

1. Cytopathic effects can include cell rounding, detachment, fusion into multinucleated cells (syncytia), and lysis.
2. They are useful for diagnosing viral infections in the laboratory as different viruses produce distinct cytopathic effects.
3. Detection of cytopathic effects requires microscopic examination of infected cell cultures.
4. Some viruses cause inclusion bodies, which are aggregates of viral particles or altered cellular material visible under a microscope.
5. The appearance and type of cytopathic effect can provide clues about the specific virus causing an infection.

Review Questions

• What are some common types of cytopathic effects observed in virus-infected cells?
• How can cytopathic effects assist in diagnosing viral infections?
• Why is microscopic examination important in detecting cytopathic effects?

Related terms

Virus Infections: Conditions caused by the invasion and replication of viruses within host organisms.

Host Cells: Cells that are infected by viruses and support their replication.

Inclusion Bodies: Aggregates of viral particles or altered cellular material within infected cells, often visible under a microscope.