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Cytopathic effects

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Cytopathic effects are observable changes in host cells due to viral infection. These changes often lead to cell damage or death.

5 Must Know Facts For Your Next Test

  1. Cytopathic effects can include cell rounding, detachment, fusion into multinucleated cells (syncytia), and lysis.
  2. They are useful for diagnosing viral infections in the laboratory as different viruses produce distinct cytopathic effects.
  3. Detection of cytopathic effects requires microscopic examination of infected cell cultures.
  4. Some viruses cause inclusion bodies, which are aggregates of viral particles or altered cellular material visible under a microscope.
  5. The appearance and type of cytopathic effect can provide clues about the specific virus causing an infection.

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