Craniates are a subphylum within the phylum Chordata that includes all animals with a skull, which protects the brain and supports sensory structures. This group encompasses a wide variety of vertebrates such as fish, amphibians, reptiles, birds, and mammals, highlighting the evolutionary significance of having a distinct cranial structure. Craniates are characterized not only by their advanced nervous systems but also by their complex organization and ability to interact more effectively with their environment compared to non-craniate chordates.