Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Columnar epithelial cells are elongated cells found lining various organs, including the digestive tract and respiratory system. They play roles in secretion, absorption, and protection.
5 Must Know Facts For Your Next Test
Columnar epithelial cells can be ciliated or non-ciliated, with cilia helping to move substances along surfaces.
Goblet cells, which secrete mucus, are often interspersed among columnar epithelial cells.
These cells form a single layer in simple columnar epithelium but can also appear in stratified layers for added protection.
Microvilli on the surface of some columnar epithelial cells increase surface area for absorption.
Columnar epithelial cells line the stomach, intestines, and parts of the respiratory tract.
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Related terms
Simple Columnar Epithelium: A single layer of tall, closely packed cells that function mainly in absorption and secretion.
Stratified Columnar Epithelium: Multiple layers of column-shaped cells that provide protection and are found in certain glands and ducts.
Goblet Cells: Specialized glandular simple columnar epithelial cells that secrete mucus to protect mucous membranes.