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Chronic infections

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Chronic infections are long-lasting infections where the virus persists in the host body, often causing continuous or recurring symptoms. These infections can evade the immune system and maintain a presence in the host for months to years.

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5 Must Know Facts For Your Next Test

  1. Chronic infections can occur when viruses integrate their genetic material into the host's genome.
  2. They often involve viruses like Hepatitis B and C, HIV, and Human Papillomavirus (HPV).
  3. Chronic infections can lead to long-term health issues such as liver cirrhosis, cancer, or immunodeficiency.
  4. These infections may be asymptomatic for extended periods before symptoms appear or reappear.
  5. Antiviral treatments can manage but not always completely eradicate chronic viral infections.

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