Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Autoimmune response is when the immune system mistakenly attacks the body’s own cells and tissues. This occurs because the body fails to distinguish between self and non-self-antigens.
5 Must Know Facts For Your Next Test
Autoimmune responses can lead to various autoimmune diseases such as rheumatoid arthritis, lupus, and type 1 diabetes.
T cells and B cells are involved in the autoimmune response by recognizing and targeting self-antigens.
Genetic factors can predispose individuals to autoimmune responses.
Environmental triggers like infections or certain drugs may initiate or exacerbate autoimmune responses.
Autoimmune responses often result in chronic inflammation and tissue damage.
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Related terms
Antigen: Any substance that causes an immune response by being recognized as foreign by the immune system.
T Cell: A type of lymphocyte that plays a central role in cell-mediated immunity.
B Cell: A type of lymphocyte involved in producing antibodies against antigens.