Autocrine signals

Definition

Autocrine signals are signaling molecules that act on the same cell that produces them. These signals play a crucial role in self-regulation and maintaining cellular functions.

5 Must Know Facts For Your Next Test

1. Autocrine signaling involves the release of molecules that bind to receptors on the same cell.
2. This type of signaling is important in processes like growth, immune responses, and cancer progression.
3. Autocrine signals can include proteins, peptides, or other small molecules.
4. Disruption in autocrine signaling pathways can lead to diseases such as cancer.
5. Examples of autocrine signals include certain cytokines and growth factors.

Review Questions

• What are autocrine signals and how do they function?
• Why are autocrine signals important in cellular regulation?
• Give an example of a molecule involved in autocrine signaling and its role.

Related terms

Paracrine Signals: Signaling molecules that act on nearby cells within the same tissue.

Endocrine Signals: Hormones released into the bloodstream to act on distant target organs.

Juxtacrine Signals: Direct cell-to-cell contact communication where the signal remains attached to the producing cell's surface.