Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Autoantibodies are antibodies produced by the immune system that mistakenly target and react with a person's own tissues or organs. This can lead to autoimmune diseases and various health complications.
5 Must Know Facts For Your Next Test
Autoantibodies are commonly associated with autoimmune diseases such as lupus, rheumatoid arthritis, and type 1 diabetes.
The presence of autoantibodies can be detected through blood tests in clinical diagnostics.
Not all autoantibodies cause disease; some may exist without leading to any noticeable symptoms.
The exact cause of autoantibody production is not fully understood but involves genetic and environmental factors.
Treatments for conditions involving autoantibodies often include immunosuppressive medications to reduce immune system activity.
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Related terms
Autoimmune Disease: A condition in which the immune system attacks the body's own tissues, mistaking them for harmful pathogens.
Immunosuppressive Medications: Drugs that inhibit or prevent activity of the immune system, often used to treat autoimmune diseases.
Antigen: A substance that triggers an immune response, typically recognized as foreign by the immune system.