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Anti-diuretic hormone (ADH)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Anti-diuretic hormone (ADH) is a peptide hormone produced by the hypothalamus and released by the posterior pituitary gland. It regulates water balance in the body by increasing water reabsorption in the kidneys.

5 Must Know Facts For Your Next Test

  1. ADH increases the permeability of the kidney's collecting ducts to water.
  2. The release of ADH is stimulated by high blood osmolarity or low blood volume.
  3. ADH acts on aquaporin channels in kidney cells to facilitate water reabsorption.
  4. Alcohol can inhibit ADH secretion, leading to increased urine production.
  5. ADH plays a crucial role in maintaining homeostasis and preventing dehydration.

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