Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Amphibolic refers to a biochemical pathway that involves both catabolic and anabolic processes. These pathways play a dual role in breaking down complex molecules for energy and using simpler molecules to synthesize cellular components.
5 Must Know Facts For Your Next Test
The citric acid cycle is an example of an amphibolic pathway, functioning in both the breakdown of carbohydrates, fats, and proteins and the production of precursors for biosynthesis.
Amphibolic pathways are crucial for maintaining metabolic balance within cells.
Key enzymes in amphibolic pathways can be regulated by energy needs and availability of substrates.
Intermediates from the citric acid cycle are used in various biosynthetic processes such as amino acid synthesis.
Amphibolic pathways integrate catabolism and anabolism, allowing organisms to efficiently adapt to varying nutritional states.
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Related terms
Catabolic Pathway: A series of reactions that break down complex molecules into simpler ones, releasing energy.
Anabolic Pathway: A set of metabolic reactions that build up complex molecules from simpler ones, requiring energy.
Citric Acid Cycle: A series of enzymatic reactions that produce energy through oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.