Acetyl CoA
from class: General Biology I Definition Acetyl CoA is a molecule that conveys carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production. It plays a crucial role in metabolism by serving as a substrate for various biochemical reactions.
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Predict what's on your test 5 Must Know Facts For Your Next Test Acetyl CoA is produced from the oxidation of pyruvate, which is derived from glycolysis. It serves as an essential substrate for the citric acid cycle, where it combines with oxaloacetate to form citrate. The formation of Acetyl CoA marks the transition between glycolysis and the citric acid cycle. Acetyl CoA plays a key role in lipid metabolism, including fatty acid synthesis and oxidation. Its production involves the enzyme complex pyruvate dehydrogenase, which catalyzes the decarboxylation of pyruvate. Review Questions What metabolic pathway does Acetyl CoA directly feed into? Which enzyme complex is responsible for converting pyruvate into Acetyl CoA? How does Acetyl CoA contribute to lipid metabolism? "Acetyl CoA" also found in:
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