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Signal transmission

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Biophysics

Definition

Signal transmission refers to the process by which cells communicate and relay information through electrical or chemical signals. This phenomenon is crucial for the functioning of excitable cells, such as neurons and muscle cells, enabling them to respond to stimuli, initiate action potentials, and propagate signals across membranes.

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5 Must Know Facts For Your Next Test

  1. Signal transmission begins with a stimulus that causes depolarization of the cell membrane, leading to the generation of an action potential.
  2. Ion channels play a key role in signal transmission by allowing ions like Na+ and K+ to flow across the membrane, altering its potential.
  3. In neurons, signal transmission can be both electrical (within the neuron) and chemical (between neurons via neurotransmitters).
  4. The speed of signal transmission is influenced by factors such as the diameter of the axon and the presence of myelin sheaths, which insulate the axon.
  5. After an action potential, the membrane undergoes repolarization to return to its resting state, readying it for another round of signal transmission.

Review Questions

  • How does depolarization initiate the process of signal transmission in excitable cells?
    • Depolarization is initiated when a stimulus causes sodium channels in the cell membrane to open, allowing Na+ ions to rush into the cell. This influx of positive charge shifts the membrane potential from its resting state towards a more positive value, triggering an action potential. Once a threshold level is reached, an all-or-nothing response occurs, leading to rapid changes in membrane permeability and subsequent signal propagation along the neuron.
  • Compare and contrast electrical and chemical signal transmission in neurons.
    • Electrical signal transmission occurs within a neuron via action potentials that travel along the axon through changes in ion permeability. In contrast, chemical signal transmission occurs at synapses where neurotransmitters are released into the synaptic cleft, binding to receptors on adjacent neurons or target cells. While electrical transmission is fast and direct, chemical transmission allows for greater flexibility and modulation of signals between cells.
  • Evaluate how myelination affects signal transmission in neurons and discuss its significance in neurological health.
    • Myelination significantly enhances signal transmission by insulating axons and facilitating saltatory conduction, where action potentials jump between Nodes of Ranvier. This increases the speed of nerve impulses and ensures efficient communication between neurons. In neurological health, demyelination can lead to disorders such as multiple sclerosis, where impaired signal transmission results in motor and sensory dysfunction. Understanding myelination's role emphasizes its importance in maintaining proper nervous system function.
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