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Facilitated diffusion

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Biophysical Chemistry

Definition

Facilitated diffusion is a type of passive transport that allows substances to cross membranes with the help of membrane proteins. This process does not require energy, as molecules move along their concentration gradient, from areas of higher concentration to areas of lower concentration. Membrane proteins play a critical role in this mechanism by providing specific pathways for various solutes, including ions and larger polar molecules, to enter or exit the cell efficiently.

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5 Must Know Facts For Your Next Test

  1. Facilitated diffusion is highly selective, meaning only specific molecules can pass through based on the type of membrane protein involved.
  2. This process occurs rapidly compared to simple diffusion due to the assistance of proteins, which can transport multiple molecules at once.
  3. Facilitated diffusion can be saturated, meaning if all available proteins are occupied, increasing the concentration of the solute will not increase the rate of transport.
  4. The rate of facilitated diffusion is influenced by factors such as temperature, pH, and the number of available transport proteins.
  5. It is essential for many cellular processes, including nutrient uptake and waste removal, ensuring cells maintain homeostasis.

Review Questions

  • How does facilitated diffusion differ from simple diffusion in terms of mechanism and efficiency?
    • Facilitated diffusion differs from simple diffusion primarily because it relies on membrane proteins to transport substances across the cell membrane. While simple diffusion allows molecules to move freely based on concentration gradients, facilitated diffusion uses specific channel or carrier proteins to assist in transporting larger or polar molecules more efficiently. This assistance increases the overall rate of transport and allows cells to regulate which substances enter or exit.
  • Discuss how the saturation of transport proteins can affect the rate of facilitated diffusion in a cell.
    • The saturation of transport proteins has a significant impact on the rate of facilitated diffusion. When all available carrier or channel proteins are occupied by their respective solutes, increasing the concentration gradient beyond a certain point will not lead to a higher rate of transport. This saturation point means that there is a limit to how fast a molecule can be transported, regardless of its concentration outside the cell. This concept highlights the importance of protein availability and regulation in cellular transport mechanisms.
  • Evaluate the implications of facilitated diffusion for cell metabolism and homeostasis within an organism.
    • Facilitated diffusion plays a crucial role in maintaining cell metabolism and homeostasis by enabling selective transport of essential nutrients and ions across cell membranes. This process ensures that cells can efficiently uptake glucose, amino acids, and ions needed for metabolic reactions while removing waste products. The efficiency and specificity provided by facilitated diffusion allow organisms to adapt to varying environmental conditions and maintain optimal internal conditions, thereby supporting overall physiological function and health.
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