Primase is an enzyme that synthesizes short RNA primers during DNA replication, serving as a starting point for DNA polymerase to begin elongating the new DNA strand. This enzyme plays a crucial role in ensuring that DNA replication occurs smoothly and accurately by providing the necessary 3' hydroxyl (OH) group for nucleotide addition. Without primase, DNA polymerase would be unable to initiate the synthesis of new DNA strands, making it essential for both leading and lagging strand synthesis.
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