To enslave means to make someone a slave, stripping them of their freedom and autonomy while subjecting them to forced labor and control by another. This concept is deeply connected to the history of exploitation and dehumanization during events like the Columbian Exchange, Spanish exploration, and conquest. The process of enslavement not only affected the individuals who were enslaved but also had profound implications for the societies involved, including the economies built on forced labor and the cultural exchanges that resulted from these brutal practices.