The term 'Father of modern political science' commonly refers to Niccolò Machiavelli, an influential Renaissance thinker known for his political writings that laid the groundwork for modern political theory. Machiavelli's most famous work, 'The Prince', emphasizes the importance of power, statecraft, and pragmatic governance, connecting deeply with the evolving political landscape of the 16th century and the rise of nation-states in Europe. His ideas challenge traditional notions of morality in politics, focusing instead on effective leadership and the realities of political power.