Charles Darwin's primary contribution to science is the theory of evolution through natural selection, which explains how species change over time and adapt to their environments. This groundbreaking idea challenged existing beliefs about creation and set the stage for modern biology, influencing various fields including genetics, ecology, and anthropology. Darwin's work not only provided a scientific framework for understanding the diversity of life but also sparked debates that would lead to the development of Social Darwinism, where his theories were misapplied to justify social hierarchies and inequalities.