Written by the Fiveable Content Team โข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโขWritten by the Fiveable Content Team โข Last updated September 2025
Definition
A transmembrane protein is a type of protein that spans across the cell membrane, with parts of it on both the inside and outside of the cell. It acts as a gatekeeper, allowing or blocking the passage of specific substances into or out of the cell.
Related terms
Ion channels: These are specific types of transmembrane proteins that form pores in the cell membrane, allowing for the selective movement of ions across the membrane.
Carrier proteins: These are another type of transmembrane proteins that bind to specific molecules and transport them across the cell membrane.
Receptor proteins: These are transmembrane proteins that receive signals from ligands (molecules) and transmit those signals into the cell, triggering various cellular responses.