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Smooth Endoplasmic Reticulum

Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examWritten by the Fiveable Content Team • Last updated September 2025

Definition

The smooth endoplasmic reticulum is a cellular organelle involved in various functions such as lipid synthesis, detoxification of drugs and toxins, and calcium storage.

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