Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Protein folding refers to the process by which a linear chain of amino acids folds into its three-dimensional shape. This shape is crucial for the protein's proper function.
Denaturation occurs when a protein loses its structure and unfolds. This can be caused by high temperatures, extreme pH levels, or certain chemicals.
Chaperones: Chaperones are proteins that assist in the correct folding of other proteins. They help prevent misfolding and aggregation.
Misfolding: Misfolding happens when a protein fails to fold correctly and adopts an abnormal structure. This can lead to diseases such as Alzheimer's or Parkinson's.