Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
piRNAs are small non-coding RNA molecules that interact with PIWI proteins to silence transposons, which are DNA sequences that can change their position within a genome. This helps maintain genomic stability.
Related terms
Transposons: These are sequences of DNA that can move or copy themselves from one location in the genome to another, potentially disrupting gene function.
Non-coding RNA: This is a type of RNA molecule that does not code for protein but has functions such as regulating gene expression.
Genomic Stability: This refers to the correct maintenance and replication of genetic material within an organism's genome, preventing mutations and other genetic damage.