Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Noncompetitive inhibitors are molecules that bind to an area other than an enzyme's active site, changing its shape so it can no longer effectively catalyze reactions with its normal substrates.
Related terms
Allosteric site: The place on an enzyme where a molecule that is not a substrate may bind, thus changing the shape of the enzyme and influencing its ability to be active.
Feedback inhibition: A method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway.
Coenzyme: A non-protein compound necessary for the functioning of an enzyme.