Noncoding Strand

Definition

The noncoding strand, also known as the template strand, is the DNA strand that serves as a template for RNA synthesis. It does not code for proteins directly but provides the sequence from which mRNA is synthesized.

Related terms

Minus Strand: This term refers to a single-stranded DNA or RNA molecule whose sequence is complementary to and synthesized from a positive or sense strand of DNA. It's like having an opposite mold for making sculptures - you need this 'negative' shape to form your desired 'positive' sculpture.

Antisense Strand: This is another name for the noncoding or template strand of DNA, which serves as a blueprint for transcribing mRNA. Imagine this as being similar to following instructions on a recipe card - you're using these guidelines (the antisense strand) to cook up something new (mRNA).

Coding Strand:

The coding strand, also known as plus or sense strand, is the DNA strand with a sequence identical to that of mRNA and codes directly for protein synthesis. It's like reading off lyrics in karaoke - what you see on screen (the coding/sense/plus stand) matches what you sing out loud (the protein).