MicroRNAs (miRNAs)

Definition

MicroRNAs are small non-coding RNA molecules that function in transcriptional and post-transcriptional regulation of gene expression.

Related terms

Gene Silencing: This is the process by which genes are turned off or 'silenced'. In our analogy, it's like when the conductor signals for certain instruments to stop playing.

RISC (RNA-induced silencing complex): This is a multiprotein complex that incorporates one strand of a small interfering RNA or microRNA molecule. It's like the baton used by our conductor - it carries out their instructions on what should be silenced.

Post-Transcriptional Regulation:

This refers to control over gene expression after the mRNA has been transcribed from DNA but before it's translated into protein. It's akin to fine-tuning how loudly each instrument plays even after they've started their piece.