Hydrophobic refers to substances that repel or do not mix with water.
Lipophilic: Refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents.
Describes substances that are attracted to water and can be dissolved by it.
Amphipathic: Refers to molecules having both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts.