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G2 Checkpoint

Definition

This checkpoint ensures that all chromosomes have been replicated without any damage before mitosis begins. It also checks that all necessary proteins are available for mitosis.

Analogy

Imagine G2 checkpoint as a final exam review session. Before you take the actual test (mitosis), you want to make sure you've studied all the material (replicated chromosomes) and have all your supplies ready (necessary proteins).

Related terms

M Phase: The phase of the cell cycle where mitosis and cytokinesis occur, resulting in cell division.

DNA Damage Response: A network of cellular pathways that detect, signal, and repair DNA lesions.

Prophase: The first stage of mitosis when chromatin condenses into visible chromosomes.

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AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.