G1 Checkpoint
Definition
This checkpoint occurs in the G1 phase of the cell cycle and checks for conditions favorable for DNA replication, including sufficient energy resources, nutrients, and absence of DNA damage.
Analogy
Consider G1 checkpoint as a bouncer at a club's entrance. It only allows entry if all conditions are met - you're dressed appropriately (no damaged DNA), you have enough money for drinks (sufficient energy resources), and it's not too crowded inside (enough nutrients).
Related terms
G0 Phase: A resting phase where cells exit from active division and enter into a quiescent state.
S Phase: The part of the cell cycle where DNA synthesis or replication takes place.
Cell Cycle Arrest: A halt in the progression through the cell cycle due to detection of abnormalities or unfavorable conditions.
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