Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
The DNA backbone refers to the sugar-phosphate chains that make up the sides of the DNA double helix. It consists of alternating deoxyribose sugar molecules and phosphate groups.
A nucleotide is a building block of DNA that consists of a sugar molecule (deoxyribose), a phosphate group, and a nitrogenous base.
Base Pairing: Base pairing refers to the specific hydrogen bonding between complementary nitrogenous bases (adenine with thymine, guanine with cytosine) in DNA molecules.