Written by the Fiveable Content Team โข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโขWritten by the Fiveable Content Team โข Last updated September 2025
Definition
Cyclic-AMP (cAMP) is a second messenger used for intracellular signal transduction, such as transferring into cells the effects of hormones like glucagon and adrenaline, which cannot pass through the plasma membrane.
Related terms
G Protein-Coupled Receptors (GPCRs): These are proteins on cell membranes that interact with signaling molecules outside the cell and trigger responses inside the cell, often involving production of cAMP.
Protein Kinase A (PKA): An enzyme activated by cAMP that regulates various cellular functions by adding phosphate groups to specific proteins.