Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Cyclic-AMP (cAMP) is a second messenger used for intracellular signal transduction, such as transferring into cells the effects of hormones like glucagon and adrenaline, which cannot pass through the plasma membrane.
Related terms
G Protein-Coupled Receptors (GPCRs): These are proteins on cell membranes that interact with signaling molecules outside the cell and trigger responses inside the cell, often involving production of cAMP.
Protein Kinase A (PKA): An enzyme activated by cAMP that regulates various cellular functions by adding phosphate groups to specific proteins.