Corepressors

Definition

Corepressors are proteins that bind to transcription factors or DNA to inhibit gene expression. They work by preventing the binding of activators or recruiting repressors to block the initiation of transcription.

Related terms

Coactivators: These are proteins that interact with transcription factors or DNA to enhance gene expression.

Repressors:

Similar to corepressors, repressors also inhibit gene expression but may not directly bind to DNA or transcription factors.

Transcription Factors:

These are proteins that bind to specific DNA sequences and regulate the rate of gene transcription.