Allosteric Regulation

Definition

Allosteric regulation is a process that can increase or decrease the activity of an enzyme by binding to a protein at a site other than its active site.

Related terms

Allosteric Site:

This is the 'switch' in our analogy - it's where a molecule that is not a substrate may bind and change the shape of an enzyme, affecting its ability to function.

Inhibitor:

This acts like something blocking access to your light switch. It's a substance that slows down or stops an enzyme's activity.

Activator:

This would be like someone helping you reach a high light switch. It's a substance that increases the activity of an enzyme.