💀anatomy and physiology i review

Thoracic Outlet Syndrome

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Thoracic outlet syndrome is a group of disorders that occur when the blood vessels or nerves in the space between the collarbone and first rib (thoracic outlet) become compressed, leading to pain, numbness, and weakness in the shoulder, arm, and hand.

5 Must Know Facts For Your Next Test

  1. Thoracic outlet syndrome can be caused by anatomical abnormalities, trauma, or repetitive movements that lead to compression of the neurovascular structures.
  2. Symptoms of thoracic outlet syndrome include pain, numbness, tingling, and weakness in the shoulder, arm, and hand, as well as discoloration and temperature changes in the affected limb.
  3. Diagnosis of thoracic outlet syndrome involves a physical examination, imaging tests, and nerve conduction studies to identify the underlying cause and extent of the compression.
  4. Treatment for thoracic outlet syndrome may include physical therapy, posture correction, anti-inflammatory medications, and, in severe cases, surgical decompression of the thoracic outlet.
  5. Prompt recognition and management of thoracic outlet syndrome is important to prevent long-term nerve damage and muscle atrophy in the affected limb.

Review Questions

  • Explain the anatomical structures involved in thoracic outlet syndrome and how their compression can lead to the characteristic symptoms.
    • Thoracic outlet syndrome involves the compression of the brachial plexus (network of nerves) and/or the subclavian artery as they pass through the thoracic outlet, the space between the collarbone and first rib. This compression can be caused by anatomical abnormalities, such as a cervical rib, or repetitive movements that lead to inflammation and swelling in the area. The compression of these neurovascular structures results in pain, numbness, tingling, and weakness in the shoulder, arm, and hand, as well as potential discoloration and temperature changes in the affected limb due to impaired blood flow.
  • Describe the diagnostic process for thoracic outlet syndrome and how the findings from various tests can help identify the underlying cause.
    • Diagnosing thoracic outlet syndrome involves a comprehensive physical examination, including assessment of range of motion, muscle strength, and provocation tests that reproduce the characteristic symptoms. Imaging tests, such as X-rays, CT scans, or MRI, may be used to look for anatomical abnormalities, like a cervical rib, that could be compressing the neurovascular structures. Nerve conduction studies and electromyography can help determine the extent and location of the nerve compression. The combination of clinical findings and diagnostic test results allows healthcare providers to identify the specific cause of the thoracic outlet syndrome, which is crucial for guiding appropriate treatment.
  • Evaluate the importance of prompt recognition and management of thoracic outlet syndrome, and discuss the potential long-term consequences if the condition is left untreated.
    • Prompt recognition and management of thoracic outlet syndrome is crucial to prevent long-term complications and disability. If left untreated, the persistent compression of the brachial plexus and subclavian artery can lead to permanent nerve damage, resulting in muscle atrophy, sensory deficits, and loss of function in the affected limb. Additionally, the impaired blood flow can cause discoloration, temperature changes, and even vascular complications, such as blood clots or aneurysms. Early intervention, which may include physical therapy, posture correction, and in severe cases, surgical decompression of the thoracic outlet, can help alleviate symptoms, restore function, and prevent irreversible damage. Therefore, recognizing the signs and symptoms of thoracic outlet syndrome and seeking prompt medical attention is crucial for maintaining optimal upper limb health and preventing long-term disability.