Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
The great saphenous vein is the longest vein in the body, running along the length of the leg from the foot to the groin. It plays a crucial role in carrying deoxygenated blood from the lower extremities back to the heart.
Related terms
Venous return: The process by which blood returns to the heart via veins.
Circulatory system: The body's system responsible for transporting blood, nutrients, gases, and waste products throughout the body.
Varicose veins: Enlarged veins that can occur when valves in the veins do not function properly, often visible on legs and feet; this condition can affect the great saphenous vein due to its size and location