Gigantism

Definition

Gigantism is a rare condition that results in abnormal growth and extreme height due to excessive secretion of growth hormone, usually caused by a benign tumor on the pituitary gland. It occurs in children or adolescents before the closure of growth plates.

Related terms

Pituitary gland: An endocrine gland about the size of a pea located at the base of the brain that produces critical hormones, including growth hormone.

Growth hormone: A protein-based hormone secreted by the anterior lobe of the pituitary gland that stimulates growth, cell reproduction, and cell regeneration in humans.

Hypothalamus: A region of the brain that controls an immense number of bodily functions including temperature regulation and release of hormones from the pituitary gland