Chief cells

Definition

Chief cells are specialized cells located in the lining of the stomach that secrete pepsinogen, an inactive enzyme that is converted into pepsin to break down proteins during digestion. They play a crucial role in the digestive process by initiating protein digestion.

Related terms

Pepsinogen: An inactive precursor of pepsin secreted by chief cells, which is activated into pepsin in the acidic environment of the stomach.

Gastric pits: Indentations in the stomach lining that contain gastric glands, including chief cells, responsible for secreting various components essential for digestion.

Protein digestion: The process of breaking down proteins into smaller peptides and amino acids, initiated by enzymes like pepsin in the stomach