Systemic circulation is the part of the cardiovascular system responsible for transporting oxygenated blood from the heart to the rest of the body and returning deoxygenated blood back to the heart. This process begins in the left ventricle, where blood is pumped through the aorta, delivering oxygen and nutrients to tissues and organs while collecting carbon dioxide and waste products for removal. The efficiency of systemic circulation relies on the heart's structure, the function of its chambers and valves, and the characteristics of blood vessels throughout the body.
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