Pericentric

Definition

Pericentric refers to a type of chromosomal inversion that includes the centromere. It involves the breakage and rearrangement of a chromosome segment that spans both arms.

5 Must Know Facts For Your Next Test

1. Pericentric inversions can alter the structure of chromosomes and potentially lead to genetic disorders.
2. Unlike paracentric inversions, pericentric inversions include the centromere.
3. Pericentric inversions can be detected using techniques such as karyotyping and fluorescence in situ hybridization (FISH).
4. These inversions may result in reduced fertility due to complications during meiosis.
5. Heterozygous individuals for pericentric inversions may produce gametes with duplications or deletions.

Related terms

Centromere:

The part of a chromosome that links sister chromatids or a pair of homologous chromosomes.

Paracentric Inversion: A type of chromosomal inversion that does not include the centromere.

Karyotyping: A laboratory technique used to visualize an individual's set of chromosomes, often used to detect chromosomal abnormalities.