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Intrapleural space

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

The intrapleural space is a thin fluid-filled cavity between the two pleural membranes surrounding the lungs. It plays a crucial role in facilitating lung expansion and contraction during breathing.

5 Must Know Facts For Your Next Test

  1. The intrapleural space contains pleural fluid which reduces friction between the lungs and chest wall.
  2. Negative pressure in the intrapleural space is essential for lung inflation.
  3. Pneumothorax occurs when air enters the intrapleural space, causing lung collapse.
  4. Pleural effusion refers to excess fluid accumulation in the intrapleural space.
  5. The balance of pressures within this space helps maintain lung stability and function.

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