European exploration of the Americas began in the late 15th century, driven by economic, religious, and political motives. Explorers like Columbus, Ponce de León, and Coronado charted new territories, while technological advancements in navigation and shipbuilding made long voyages possible. The arrival of Europeans had profound impacts on Native American populations, including disease, displacement, and cultural changes. Early colonial settlements like Jamestown and Plymouth struggled initially but laid the foundation for the Thirteen Colonies, which developed diverse economic systems and governance structures.