How could an innovative experiment be designed to assess whether prenatal stress exposure contributes to the development of neurodevelopmental disorders? Using cross-sectional studies comparing adults diagnosed with neurodevelopmental disorders against those without, asking about their mothers' prenatal stress levels. Conducting case-study research on families where mothers experienced significant stress during pregnancies that resulted in children with neurodevelopmental disorders. Evaluating rates of neurodevelopmental disorders in different geographic locations. Comparing outcomes from cohort studies of children whose mothers reported high levels of stress during pregnancy with those who did not.